Title | Link | Year | Patient | Area of disease | Treatment | Source | Authors | Clinic | Free Article | Pay Article | Note |
Chylothorax in Gorham's syndrome. A common complication of a rare disease |
Abstract Full Article (PDF) |
1994 |
Case 1: male, 30 years Case 2: male, 18 years |
Case 1: Thorax, ribs Case 2: Thorax, ribs, left scapula, clavicle, proximal humerus, and first rib |
Chest, Vol 105, 208-213 | ML Tie, GA Poland and EC Rosenow 3rd | Division of Internal Medicine, Mayo Clinic, Rochester, MN 55905 | X | Contains a list of 24 case reports of patients with Gorham's Syndrome and associated Chylothorax from 1954 to 1993. | ||
A Case of Gorham’s Disease with Chylothorax Treated Curatively with Radiation Therapy |
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2005 | female, 31 years | right scapula, multiple thoracic and lumbar vertebral bodies, and multiple ribs on the right side | Clinical Medicine &: Research Volume 3, Number 2: 83-86 | Bethany M. Duffy, BA; Rafael Manon, MD; Rakesh R. Patel, MD; and James S. Welsh, MD | University of Wisconsin Cancer Center | X | |||
Seltene Differenzialdiagnose eines Chylothorax | Abstract | 2007 | male, 17 years | thorax wall | Pneumologie 2008; 62: 196-199 | J. Bernstein, M. Engelhardt, S. Retzlaff | Klinik für Pneumologie, HELIOS Kliniken Schwerin | X | German text | ||
Platelet-derived growth factor receptor-beta in Gorham's disease |
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2006 | male, 17 years | spine, ribs | Spine stabilization, thalidomide, celecoxib, interferon-alpha2b, pamidronate, zoledronate, thoracotomy, pleurectomy, talc pleurodesis, and imatinib mesylate | Nature Clinical Practice Oncology (2006) 3, 693-697 | Jeroen Hagendoorn, Timothy P Padera, Torunn I Yock, G Petur Nielsen, Emmanuelle di Tomaso, Dan G Duda, Thomas F Delaney, Henning A Gaissert, Jennifer Pearce, Andrew E Rosenberg, Rakesh K Jain and David H Ebb | Harvard Medical School, Boston, MA, USA | X | ||
Interleukin-6: a potential mediator of the massive osteolysis in patients with Gorham-Stout disease | Full Article (PDF) | 1996 | male, 9 years | resorption of mandible, extended to maxilla, zygoma, right parietal region, and cranium | calcitonin and bisphosphonates (pamidronate), radiation | Journal of Clinical Endocrinology and Metabolism Vol. 81, No. 5, 1996 | Rowena D. Devlin, Henry G. Bone III, and G. David Roodman | University of Texas, USA | X | ||
Chylothorax associated with massive osteolysis (Gorham's syndrome) |
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2001 | male, 15 years | parietal and visceral pleura, ribs | Thoracic duct ligation | Ann Thorac Surg 2002;73:1956–7 | Koichi Fujiu, MD, Ryuzo Kanno, MD, Hiroyuki Suzuki, MD, Naoya Nakamura, MD, and Mitsukazu Gotoh, MD | First Departments of Surgery and Pathology, Fukushima Medical University, Fukushima, Japan | X | patient died of lymphocytopenia | |
Case 92: Gorham Syndrome |
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2004 | female, 31 years | anterior mediastinum, pleural surfaces, adjacent to upper posterior ribs and the thoracic spine, extending from the hila into the lung parenchyma | bilateral chest tubes, two rounds of pleurodesis with talc, pericardial drainage, total parenteral nutrition, and 33-Gy external beam radiation therapy in the mediastinum | Radiology: Volume 238: Number 3—March 2006 | Jannette Collins, MD | Department of Radiology, University of Wisconsin | X | ||
The Phantom |
Full Article (PDF) |
1998 | male, 19 years | ribs | radiotherapy, surgical dissection of the thoracic duct and partial pleurectomy, bisphosphonates | Respiration 1998;65:417–420 | L. Plasswilma, I. Hennig, M. Spoendlin, W. Wegmann | Department of Radiology, University Hospital, Basel, University Department of Internal Medicine, Kantonsspital Bruderholz, and Institute of Pathology, Liestal, Switzerland | X | radiographic and clinical examinations have indicated arrest of the bone resorption | |
Gorhams Disease Complicated by Chyloma of the Chest Wall |
Abstract Full Article (PDF) |
2006 | male, 22 years | anterior mediastinum, cystic lesion along the posterior chest wall, vertebral bodies | thoracic surgery, pleurodesis by OK432 streptococcal preparation | The Japanese Journal of Thoracic and Cardiovascular Surgery 2006; 54: 311–313 | Akihiko Kitami, MD, Takashi Suzuki, MD, Shuichi Suzuki, MD, Ryosuke Usuda, MD, Yoshito Kamio, MD and Mitsutaka Kadokura, MD | Respiratory Disease Center, Showa University, Japan | X | A two-year follow up did not show any reoccurrence of the chylothorax. | |
Chylothorax in Gorham's Disease |
Full Article (PDF) |
2002 | female, 25 years old | ribs, vertebral bodies | radiotherapy, pleurodesis with OK-432 | J Korean Med Sci 2002; 17: 826-9 | Won Sup Lee, Sung Han Kim, Inho Kim, Hark Kyun Kim, Keun Seok Lee, Sang Yoon Lee, Dae Seog Heo, Bong-Soon Jang, Yung-Jue Bang, Noe Kyeong Kim | Department of Internal Medicine, and Orthopedic Surgery., Cancer Research Institute, Seoul National University, Korea | X | Even though there was no definite response to radiotherapy and pleurodesis, the patient showed stable condition up to 20 months after diagnosis. | |
The Gorham-Stout syndrome (Gorham’s massive osteolysis) - A REPORT OF SIX CASES WITH HISTOPATHOLOGICAL FINDINGS |
Abstract Full Article (PDF) |
1998 |
Case 1: female, 77 years Case 2: female, 70 years Case 3: female, 19 years Case 4: female, 78 years Case 5: female, 83 years Case 6: female, 56 years |
various | suggest bisphosphonates or calcitonin | THE JOURNAL OF BONE AND JOINT SURGERY 1999;81-B:501-6. | G. Möller, M. Priemel, M. Amling, M. Werner, A. S. Kuhlmey, G. Delling | Hamburg University School of Medicine, Hamburg, Germany | X | Study provides good evidence of hyperactive osteoclastic bone resorption causing osteolytic changes. It seems reasonable to suggest that antiresorptive therapy, for example with bisphosphonates or calcitonin, started in an early phase of the disease, could lead to a dramatic improvement in the treatment of progressive osteolytic changes. |